Sleep-Disordered Breathing
نویسندگان
چکیده
Objective: The purpose of this study was to assess sleep and breathing in patients with amyotrophic lateral sclerosis (ALS) with bulbar muscle involvement. Design: Prospective, controlled study of sleep and breathing measured during polysomnography. Setting: University teaching hospital and referral center. Patients: Patients with definite ALS and healthy age-matched control subjects. Interventions: Eighteen ALS patients and 10 age-matched control subjects underwent one night of polysomnography. Thirteen patients with ALS were studied for a second night. Results: The ALS patients had more arousals per hour (p=0.008), more stage 1 sleep (p=0.01), and a shorter total sleep time (TST) (279±69 vs 331.4±55.9 min, mean±SD, p=0.04) than the control subjects. The ALS patients had mild sleep-disordered breathing with a greater apnea/hypopnea in¬ dex (AHI) than the control subjects (p=0.005). On the second night ofpolysomnography, there was
منابع مشابه
Sleep-disordered breathing in alcoholics: association with age.
Sleep apnea and related disorders are not uncommon in abstinent alcoholics. We assessed the relationship between age and the presence and severity of sleep-disordered breathing in alcoholism by performing one night of polysomnography on 75 abstinent alcoholic subjects undergoing treatment for alcoholism. Sleep-disordered breathing (defined as 10 or more apneas plus hypopneas/hr of sleep) was pr...
متن کاملSleep-disordered breathing in alcoholics.
Sleep apnea and related disorders contribute to disturbed sleep in abstinent alcoholics. In an earlier report from our group, sleep-disordered breathing was common and increased with age in a cohort of 75 abstinent alcoholics. We now report an extension of the previous work that includes studies of an additional 103 abstinent alcoholics undergoing treatment for alcoholism (total sample = 188) a...
متن کاملSleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women.
CONTEXT Sleep-disordered breathing (characterized by recurrent arousals from sleep and intermittent hypoxemia) is common among older adults. Cross-sectional studies have linked sleep-disordered breathing to poor cognition; however, it remains unclear whether sleep-disordered breathing precedes cognitive impairment in older adults. OBJECTIVES To determine the prospective relationship between s...
متن کاملSleep-Disordered Breathing in Children With Metabolic Syndrome: The Role of Leptin and Sympathetic Nervous System Activity and the Effect of Continuous Positive Airway Pressure
OBJECTIVE The purpose of this work was to determine whether, in children with metabolic syndrome and sleep-disordered breathing, metabolic markers separate them from children with metabolic syndrome without sleep-disordered breathing and whether treatment of sleep-disordered breathing with continuous positive airway pressure is associated with an improvement in metabolic derangement. PATIENTS...
متن کاملInvited Review HIGHLIGHTED TOPIC Physiology and Pathophysiology of Sleep Apnea Influence of cardiac function and failure on sleep-disordered breathing: evidence for a causative role
Caples, Sean M., Robert Wolk, and Virend K. Somers. Influence of cardiac function and failure on sleep-disordered breathing: evidence for a causative role. J Appl Physiol 99: 2433-2439, 2005; doi:10.1152/japplphysiol.00676.2005.— Heart failure is an increasingly common public health problem that is strongly linked to both central and obstructive sleep apnea, collectively referred to as sleep-di...
متن کاملDaytime predictors of sleep disordered breathing in children and adolescents with neuromuscular disorders.
Sleep disordered breathing with or without nocturnal hypercapnic hypoventilation is a common complication of respiratory muscle weakness in childhood neuromuscular disorders. Nocturnal hypercapnic hypoventilation as a sign of respiratory muscle fatigue, portends a particularly poor prognosis. We aimed at identifying daytime predictors of sleep disordered breathing at its onset and sleep disorde...
متن کامل